Ceremonial cacao is increasingly used as a natural support for emotional well-being. It contains bioactive compounds that can enhance happiness and reduce stress. But what if you are taking antidepressants? Is it safe to drink ceremonial cacao, or are there risks? Since I have personally dealt with this topic, I wanted to provide a clear overview to help others make informed decisions.
In this article, we’ll explore how cacao affects the brain, potential interactions with antidepressants, and how you can enjoy it safely—based on scientific insights.
How Does Ceremonial Cacao Affect Your Mood?
Ceremonial cacao is packed with natural compounds that gently but noticeably influence your emotions.
1. Theobromine – Gentle Energy Without Jitters
Unlike coffee, cacao contains no caffeine but instead theobromine—a natural stimulant that provides energy without making you feel anxious or overstimulated. At the same time, it dilates blood vessels and improves oxygen supply to the brain. Research suggests that theobromine can support cognitive function, making it particularly interesting for individuals experiencing fatigue or low mood.
2. Anandamide – The “Bliss Molecule”
Anandamide interacts directly with cannabinoid receptors in the brain, the same receptors activated by CBD or cannabis. The result? A natural, gentle euphoria that promotes relaxation and emotional balance. Scientists have identified anandamide as a key player in mood regulation.
3. Tryptophan – The Natural Serotonin Booster
Tryptophan is an essential amino acid that your body needs to produce serotonin—a neurotransmitter that positively influences mood. Ensuring adequate tryptophan intake can support emotional well-being and help alleviate depressive symptoms.
4. MAO Inhibitors – Keeping Neurotransmitters Active Longer
An interesting aspect of cacao is its natural MAO inhibitors. These slow the breakdown of important neurotransmitters like serotonin, dopamine, and norepinephrine, prolonging their effects in the brain. This may have a positive impact on mood and emotional well-being.
If you want to learn more about the effects of ceremonial cacao on mental health, click HERE.
Can You Combine Ceremonial Cacao with Antidepressants?
The answer is: it depends. The type of medication you take plays a crucial role. Here’s an overview:
1. SSRIs (e.g., Fluoxetine, Sertraline, Escitalopram)
SSRIs increase serotonin levels in the brain. Cacao does too—but through a different mechanism. Combining both could, in extreme cases, lead to excessive serotonin levels, a condition known as serotonin syndrome. Though rare, it is serious and can cause symptoms such as restlessness, tremors, or rapid heartbeat.
➡ Tip: If you take SSRIs, start with a small amount of cacao (e.g., 10–15 g instead of the usual 30–40 g) and listen to your body.
2. MAO Inhibitors (e.g., Tranylcypromine, Phenelzine)
These medications block the enzyme that breaks down neurotransmitters—just like the natural MAO inhibitors in cacao. Combining the two can lead to dangerous blood pressure spikes. Some studies suggest that foods with natural MAO inhibitors, such as cacao or fermented foods, can be problematic.
🚫 Warning: If you take MAO inhibitors, it’s best to avoid ceremonial cacao.
3. Atypical Antidepressants (e.g., Bupropion, Mirtazapine, Tianeptine)
These medications primarily affect dopamine or norepinephrine rather than serotonin. There are fewer direct interactions with cacao, but theobromine can increase heart rate, which, in combination with certain antidepressants, might cause restlessness.
➡ Tip: If you feel uneasy after consuming cacao, reduce the amount or avoid it.
How to Safely Enjoy Ceremonial Cacao
If you take antidepressants and still want to enjoy cacao, consider these precautions:
🔹 Start slow: Begin with a small amount (e.g., 10 g) and observe how you feel.
🔹 Watch for symptoms: If you feel restless, jittery, or unwell, lower the dose or take a break.
🔹 Avoid MAO inhibitors: If you take these medications, cacao is not a good idea.
🔹 Consult your doctor: If unsure, ask your physician or therapist whether ceremonial cacao is safe for you.
